SGS, the world’s leading testing, inspection and certification company, has announced the release of a new white paper, ‘3D reconstructed skin models: transforming clinical and safety testing’.

Targeted at researchers, toxicologists and formulation scientists in the clinical and dermatological fields, the white paper provides essential insights into how advanced in vitro skin and mucosal tissue systems are reshaping research and development practices.

As demand grows for ethical, human-relevant alternatives to animal testing, reconstructed human epidermis (RHE) and reconstructed mucosal epithelium models are emerging as essential tools for safety assessment, product development and regulatory compliance. These biologically advanced systems closely mimic human tissue, supporting validated, reproducible testing across irritation, absorption and disease modeling studies.

The white paper explores:

• The evolution of 3D skin and epithelium models
• Key applications in dermatology, toxicology and drug development
• Validation requirements and regulatory alignment with OECD guidelines
• How multiparametric approaches can strengthen data quality and product safety claims

Download ‘3D reconstructed skin models: Transforming clinical and safety testing’ to discover how advanced in vitro skin and mucosal tissue systems are driving safer, more ethical and scientifically robust approaches in clinical research and product development.